Recombinant Cynomolgus monkey CD86 Protein

• Cat.No.: CD86-592C
• Product Overview: Recombinant Cynomolgus monkey CD86 protein without tag was expressed in HEK293.

Specification

• Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
• Source: HEK293
• Species: Cynomolgus monkey
• Form: Lyophilized
• Molecular Mass: 27.3 kDa
• Protein length: 324
• AA Sequence: TMGLSNTLFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNRSLSELVVFWQNQENLVLNEVYLGKEKFDSVHSKYMGRTSFDPESWTLRLHNLQIKDKGLYQCIIHHKRPTGMIRIHQMNSELSVLANFSQPEIVPISNITENMYINLTCSSIHGYPEPEKMSVLLRTKNSTIEYDGVMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCVLETDKTQLLSSPFSIELEDPQPPPDHIPWITAVLPTVIICVMAFCLILWKWKKKKQPRNSYKCGTNTMEREESEQTKKREKINVPERSDEAQCVFKSLKTPSCDKSDTRF
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: CD86 CD86 molecule [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CD86
• Synonyms: CD86; CD86 molecule; T-lymphocyte activation antigen CD86; CD86 antigen
• Gene ID: 714390
• mRNA Refseq: NM_001042644
• Protein Refseq: NP_001036109
• UniProt ID: Q9BDM4