Recombinant COVID-19 N protein truncated N04, His-tagged

• Cat.No.: N04-131V
• Product Overview: Recombinant COVID-19 N protein truncated N04 was fused to His-tag at the N-terminus and expressed in E.coli.

Specification

• Species: COVID-19
• Source: E.coli
• Tag: His
• Description: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
• Form: Liquid in sterile PBS, pH7.4.
• Endotoxin: <1.0 EU per μg protein as determined by the LAL method.
• Purity: >95% as determined by SDS-PAGE.

Gene Information

• Gene Name: N
• Official Symbol: N
• Synonyms: GU280_gp10
• Gene ID: 43740575
• Protein Refseq: YP_009724397.2