Recombinant COVID-19 N protein (nucleocapsid phosphoprotein), Flag-tagged

• Cat.No.: N-128V
• Product Overview: Recombinant COVID-19 N protein (nucleocapsid phosphoprotein) was fused to Flag(DYKDDDDK) tag and expressed in Human cells.

Specification

• Species: Sars-CoV-2
• Source: Human Cells
• Description: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
• Form: Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives.
• Molecular Mass: 49.4 kDa
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining.
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Gene Information

• Gene Name: N
• Official Symbol: N
• Synonyms: GU280_gp10
• Gene ID: 43740575
• Protein Refseq: YP_009724397.2