Recombinant Bovine Prion Protein (T194A), His-tagged

• Cat.No.: Prnp-800B
• Product Overview: Recombinant Bovine Prion Protein (T194A) was expressed in E. coli with His tag.

Specification

• Species: Bovine
• Source: E.coli
• Tag: His
• Description: N-terminal His-tagged mutant (T194A) mature PrPc. The protein may be reconstituted in detergent-containing buffers e.g. TX-100 (0.5%) or under mild denaturing conditions (e.g. 1.5 M guanidine-HCl or urea). The bovine PrPc (T194A) is a homologue to the disease-associated human (T183A) point mutation. It may be used as substrate to investigate the effect of this mutation for protein stability in in vitro/in vivo conversion studies.
• Form: Lyophilized from 10 mM Tris-HCl pH 6.7
• Purity: > 95 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: PRNP prion protein [ Bos taurus (cattle) ]
• Official Symbol: Prnp
• Synonyms: PrP; AltPrP
• Gene ID: 281427
• mRNA Refseq: AB001468.1
• Protein Refseq: ABE02802.1
• UniProt ID: P10279