Recombinant Betula pendula Bet v 1 Protein, His-tagged

• Cat.No.: Bet v 1-09B
• Product Overview: Recombinant Betula verrucosa (European white birch) allergen 1-A with a C-terminal His-tag produced in Nicotiana benthamiana by Agrobacterium-mediated transient expression.

Specification

• Species: Betula pendula
• Source: Nicotiana Benthamiana
• Tag: His
• Description: Birch trees (Betula), are found in the temperate climate zone of the northern hemisphere and release large amounts of pollen during spring, a major cause of allergic rhinitis in Europe. A 17 kDa protein called Bet v 1-A is the major allergen of birch pollen. It has been shown that in birch-rich areas of Scandinavia, >95% of birch pollen allergic patients have immunoglobulin E (IgE)-binding to Bet v 1. Three regions on the surface of the protein contain cross-reactive B-cell epitopes that provide structural basis for similar allergic symptoms when encountering pollens from related trees such as hazel and alde.
• Form: Lyophilized
• Molecular Mass: 18.6 kDa
• Purity: 98%
• Storage: Lyophilized materials are stable for up to twelve months from date of receipt at -70 centigrade.
  It is recommended that reconstituted protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM HEPES pH7.5, 100 mM NaCl, 175 mM Trehalose Dihydrate.

Gene Information

• Official Symbol: BETVIA
• Synonyms: BETVIA; Major pollen allergen Bet v 1-A; BETVI; Allergen Bet v I-A; Allergen: Bet v 1-A
• UniProt ID: P15494