Recombinant Anti-Human CSF2RA Antibody Fragment scFv, CD116

Antigen Description :

Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

Target :

CSF2RA

Immunogen :

Human GM-CSF Receptor alpha transfected COS cells.

Expression Host :

E.coli

Type :

scFv

Source :

Culture supernatant

Species :

Human

Clone :

CD116

Conjugation :

His tagged

Applications :

Suitable for use in ELISA, western blot, immunohistochemistry, flow cytometry, immunoaffinity purification and most other immunological methods.

Storage :

Store it under sterile conditions at -20 ºC upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Stability :

Samples are stable for up to twelve months from date of receipt at -20ºC and are stable for six months at 4 ºC.

Background :

Introduction

Monoclonal antibody Fragment binds to CSF2RA, for treatment of rheumatoid arthritis.

Gene Name	CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) [ Homo sapiens ]
Official Symbol	CSF2RA
Synonyms	CSF2RA; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); GMR; CD116; CSF2R; SMDP4; CDw116; CSF2RX; CSF2RY; GMCSFR; CSF2RAX; CSF2RAY; GM-CSF-R-alpha; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GMCSFR-alpha; CD116 antigen; GM-CSF receptor alpha subunit; colony stimulating factor 2 receptor alpha subunit; granulocyte-macrophage colony-stimulating factor receptor alpha chain
Gene ID	1438
mRNA Refseq	NM_001161529
Protein Refseq	NP_001155001
MIM	306250
UniProt ID	P15509
Chromosome Location	Xp22.32 and Yp11.3
Pathway	Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Immune System; Interleukin receptor SHC signaling; Interleukin-2 signaling; Interleukin-3, 5 and GM-CSF signaling;
Function	cytokine receptor activity; receptor activity

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