Recombinant Anti-Human CSF2RA Antibody Fragment scFv, CD116

• Cat.No.: MOM-18096-S(P)
• Product Overview: Recombinant antibody Fragment scFv to CSF2RA.

Specification

• Species: Human
• Tag: His
• Antigen Description: Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
• Target: CSF2RA
• Immunogen: Human GM-CSF Receptor alpha transfected COS cells.
• Expression Host: E.coli
• Type: scFv
• Clone: CD116
• Conjugation: His tagged
• Applications: Suitable for use in ELISA, western blot, immunohistochemistry, flow cytometry, immunoaffinity purification and most other immunological methods.
• Storage: Store it under sterile conditions at -20 ºC upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
• Stability: Samples are stable for up to twelve months from date of receipt at -20ºC and are stable for six months at 4 ºC.
• Introduction: Monoclonal antibody Fragment binds to CSF2RA, for treatment of rheumatoid arthritis.

Gene Information

• Gene Name: CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) [ Homo sapiens ]
• Official Symbol: CSF2RA
• Synonyms: CSF2RA; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); GMR; CD116; CSF2R; SMDP4; CDw116; CSF2RX; CSF2RY; GMCSFR; CSF2RAX; CSF2RAY; GM-CSF-R-alpha; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GMCSFR-alpha; CD116 antigen; GM-CSF receptor alpha subunit; colony stimulating factor 2 receptor alpha subunit; granulocyte-macrophage colony-stimulating factor receptor alpha chain
• Gene ID: 1438
• mRNA Refseq: NM_001161529
• Protein Refseq: NP_001155001
• MIM: 306250
• UniProt ID: P15509
• Chromosome Location: Xp22.32 and Yp11.3
• Pathway: Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Immune System; Interleukin receptor SHC signaling; Interleukin-2 signaling; Interleukin-3, 5 and GM-CSF signaling
• Function: cytokine receptor activity; receptor activity