Recombinant 2019-nCoV RdRp Protein, His-tagged

• Cat.No.: RdRp-01C
• Product Overview: Recombinant 2019-nCoV RNA-dependent RNA polymerase (RdRp) was expressed in E. coli cells using a C-terminal His tag.

Specification

• Species: Sars-Cov-2
• Source: E.coli
• Tag: His
• Description: A novel coronavirus (SARS-CoV-2) has caused a global COVID-19 pandemic of respiratory disease in 2020. RNA-dependent RNA polymerase (RdRp) is an enzyme that is crucial to life cycle of RNA viruses including coronaviruses. RdRp catalyzes the synthesis of viral RNA, thereby playing a central role in the replication and transcription cycle of COVID-19 viruses, possibly in complex with nsp7 and nsp8. Therefore, RdRp is a prime target for nucleotide analog antiviral inhibitors, such as remedesivir, for development of new antiviral therapeutics.
• Molecular Mass: ~100 kDa
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.