Pyrroline-5-carboxylate Reductase 1
Cat.No. : | CBCRY27 |
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Source : | E.coli |
Tag : | Non |
Background : | Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor. The enzymatic cycle between P5C and proline is very important for the regulation of amino acid metabolism, intracellular redox potential, and apoptosis. |
Protein Classification : | Oxidoreductase |
Structure Weight : | 168155.50 Da |
Polymer : | 1 |
Molecule : | Pyrroline-5-carboxylate reductase 1 |
Chain Length : | 321 amino acids |
PDB ID : | 2GER |
MMDB ID : | 41542 |
Method : | X-Ray Diffraction |
Resolution : | 3.1Å |
Reference : | Meng, Z., Lou, Z., Liu, Z., Li, M., Zhao, X., Bartlam, M., Rao, Z. (2006) Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol. 359: 1364-1377 |
Gene Name | PYCR1 |
Synonyms | P5C; P5CR; PIG45; PP222; PYCR; P5C reductase; proliferation-inducing protein 45; pyrroline-5-carboxylate reductase 1; EC 1.5.1.2; P5C reductase 1; P5CR1 |
UniProt ID | P32322 |
Gene ID | 5831 |
Chromosome Location | 17q25.3 |
Function | binding; oxidoreductase activity; pyrroline-5-carboxylate resuctase activity |
◆ Recombinant Proteins | ||
PYCR1-6125H | Recombinant Human PYCR1 Protein (Ser2-Asp319), N-His tagged | +Inquiry |
PYCR1-31273TH | Recombinant Human PYCR1, His-tagged | +Inquiry |
Pycr1-5270M | Recombinant Mouse Pycr1 Protein, Myc/DDK-tagged | +Inquiry |
PYCR1-1815H | Recombinant Human PYCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR1-3175H | Recombinant Full Length Human PYCR1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PYCR1-1448HCL | Recombinant Human PYCR1 cell lysate | +Inquiry |
Not For Human Consumption!
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