Native Toxoplasma Gondii Deoxycholate Lysate, RH strain

• Cat.No.: Deoxycholate-03T
• Product Overview: A concentrated source of Toxoplasma gondii tachyzoite antigens, lysed and inactivated with deoxycholate buffer. This product was manufactured and tested in accordance with established procedures.

Specification

• Description: Toxoplasma gondii (T. gondii) is an obligate intracellular parasitic protozoan of the phylum Apicomplexa. It is the causative agent of the disease Toxoplasmosis, a common parasitic zoonoses which is widespread throughout most of the world. The domestic cat and other members of the family Felidae are the only definitive hosts for T.gondii. However, T.gondii is also capable of infecting a wide range of birds and mammals, including humans, which act as intermediate hosts. In domestic cats, sexual replication of T. gondii occurs with the release of oocysts into the environment, in cat faeces. In humans, T. gondii is primarily acquired by ingesting undercooked meat contaminated with bradyzoites (tissue cysts), drinking water contaminated by oocysts, or via accidental ingestion of cat faeces containing oocysts. In pregnant women, infected with T. gondii, vertical transmission of the parasite can occur causing congenital defects, stillbirths or miscarriage. In rare cases, infection via blood transfusion and organ transplant can also occur (CDC).
• Species: T. Gondii, Strain RH
• Form: Liquid, Lysed and inactivated with deoxycholate buffer
• Storage: Store frozen at less than -60 centigrade. Can be frozen, but avoid multiple freeze-thaw cycles
• Concentration: 1.88 mg/mL
• Storage Buffer: Presented as liquid in 40mM glycine, 274mM NaCl with 1% Sodium Deoxycholate pH 9.0
• References: 1. Centers for Disease Control and Prevention: Parasites – Toxoplasmosis (Toxoplasma infection)
  2. Black MW, Boothroyd JC. 2000. Lytic cycle of Toxoplasma gondii. Microbiol Mol Biol Rev. Sep;64(3):607-23.

Gene Information

• Official Symbol: Deoxycholate
• Synonyms: Deoxycholate