Native Mouse/Rat PLP (139-151) Protein

• Cat.No.: PLP-21
• Product Overview: Purified myelin proteolipid protein (PLP) for PLP-induced EAE models in mouse and rat.

Specification

• Species: Mouse/Rat
• Description: Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). The main characteristics of the disease are focal areas of demyelination and inflammation, however the pathogenesis is unclear.
  Although no animal model thus far establishes all facets of human MS, Experimental Autoimmune Encephalomyelitis (EAE) represents the model most studied for the disease. Initially brain homogenates were used as antigens for immunization. Today, myelin related proteins or peptides are used in the disease.
• Form: Lyophilized, 15 mg/vial
• Molecular Mass: 1537.79
• Purity: ≥ 98% (HPLC)
• Applications: Multiple Sclerosis: PLP 139-155 induced experimental autoimmune encephalomyelitis (EAE) rodent models.
• Storage: Storage at -20 centigrade.
• Shipping: Shipping at ambient temperature.

Gene Information

• Official Symbol: PLP
• Synonyms: Myelin Proteolipid Protein; PLP1; Lipophilin; PLP