Native Mouse Apotransferrin

• Cat.No.: Trf-70M

Specification

• Species: Mouse
• Source: Mouse Plasma
• Tag: Non
• Description: Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
• Form: Lyophilized
• Molecular Mass: 80.0 kDa
• Purity: Purity by SDS-PAGE: ≥98%
• Usage: For Research Use Only! Not For Use in Humans.
• Notes: Centrifuge the vial prior to opening
• Storage: -20°C
• Storage Buffer: Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
• Shipping: Gel pack

Gene Information

• Gene Name: Trf transferrin [ Mus musculus ]
• Official Symbol: Trf
• Synonyms: HP; Tf; Tfn; hpx; Cd176; AI266983; serotransferrin; siderophilinbeta-1 metal-binding globulin; hypotransferrinemia with hemochromatosis
• Gene ID: 22041
• mRNA Refseq: NM_133977
• Protein Refseq: NP_598738
• UniProt ID: Q921I1
• Chromosome Location: 9 F1-F3; 9 55.03 cM
• Pathway: HIF-1 signaling pathway, organism-specific biosystem; Iron Homeostasis, organism-specific biosystem; Mineral absorption, organism-specific biosystem
• Function: ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding; metal ion binding; protein binding