Native Human T-Lymphotropic Virus Type II, Inactivated, Tag Free

• Cat.No.: HTLV-II-16H
• Product Overview: 10,000× concentrate of HTLV-II viral lysate prepared from Prostak-filtered/centrifuged material and inactivated with 22% Non-idet P40 detergent and 5M NaCl.

Specification

• Species: HTLV-II
• Source: BJAB cells
• Tag: Non
• Description: Human T-lymphotropic virus type 1 (HTLV-1) is a complex leukemogenic retrovirus with a single-stranded positive sense RNA genome that expresses unique proteins with oncogenic potential. There are four known strains of HTLV, of which HTLV-1 and HTLV-2 are the most prevalent worldwide. HTLV-1 was originally identified in 1980 in a T-cell line derived from a patient with cutaneous T-cell lymphoma (Hinuma et al., 1981) and was also detected in adult T-cell leukemia (ATL) patients (Yoshida et al., 1982; Kalyanaraman et al., 1982). Subsequently, HTLV-2 was identified in a cell line derived from a patient with a variant form of hairy T-cell leukemia (Saxon et al., 1978a,b; Boxus et al., 2008). Since then, HTLV-2 has not been associated with leukemia/lymphoma; nevertheless, it has been associated with a few sporadic cases of neurological disorders.
• Tag: Non
• Reactivity: Verification of Inactivation ≥ 95%, Western Blot bands p24 and gp46 are present
• Storage: -60 centigrade or below
• Concentration: Approximately 4 mg/mL
• Storage Buffer: TNE (Tris, NaCl, EDTA) Buffer, pH 7.02-7.35 and 0.6% NP-40

Gene Information

• Official Symbol: HTLV-II
• Synonyms: HTLV-II; Human T-Lymphotropic Virus Type II