Native Human PYGB Protein

• Cat.No.: PYGB-03H
• Product Overview: Native human PYGB protein purified from human heart tissue. Blood sample from the tissue donor was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, and HCV.

Specification

• Description: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
• Source: Heart
• Species: Human
• Purity: > 95% (SDS-PAGE)
• Storage: At -20 centigrade(between -15 and -30 centigrade allowed)
• Storage Buffer: Solution in 1 mM β-glycerophosphate, 1 mM EDTA, 15 mM ME, 0.5 M NaCl, pH 7.8, and 50 % glycerol.

Gene Information

• Gene Name: PYGB glycogen phosphorylase B [ Homo sapiens (human) ]
• Official Symbol: PYGB
• Synonyms: PYGB; glycogen phosphorylase B; GPBB; glycogen phosphorylase, brain form; phosphorylase, glycogen; brain; EC 2.4.1.1
• Gene ID: 5834
• mRNA Refseq: NM_002862
• Protein Refseq: NP_002853
• MIM: 138550
• UniProt ID: P11216