Native Human Immunoglobulin G1 (IgG1)

• Cat.No.: IgG1-227H

Specification

• Species: Human
• Source: Human Myeloma Plasma
• Tag: Non
• Description: Crystallizable fragments composed of the carboxy-terminal halves of both Immunoglobulins Heavy Chains linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (Complement fixation, binding to the cell membrane via FC Receptors, and placental transport). IgG1 FC was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
• Form: Frozen
• Molecular Mass: MW: 50,000 Da by SDS-PAGE
• Purity: >=95% by SDS-PAGE.
• Usage: For research use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <=>
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, with 200 mM NaCl and 0.05% NaN3