Native Human Haptoglobin 2-2

• Cat.No.: Hp2-2-196H
• Product Overview: Purified Native Human Plasma Haptoglobin 2-2

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen).In clinical settings, the haptoglobulin assay is used to screen for and monitor intravascular hemolytic anemia . In intravascular hemolysis, free hemoglobin will be released into circulation and hence haptoglobin will bind the Hb. This causes a decline in Hp levels. Conversely, in extravascular hemolysis the reticuloendothelial system, especially splenic monocytes, phagocytose the erythrocytes and hemoglobin is not released into circulation; serum haptoglobin levels are therefore normal
• Form: Lyophilized, salt-free
• Molecular Mass: 170,000-900,000
• Purity: >95% by SDS-PAGE
• Storage: Store at -20 °C.