Native Human Growth Hormone 1

• Cat.No.: GH1-5354H
• Product Overview: Native Human GH1 isprepared from Human pituitary glands.

Specification

• Species: Human
• Source: Human Pituitary Gland
• Tag: Non
• Description: Human GH1, a protein hormone from the anterior lobe of thepituitary gland, comprises a single polypeptide chain of 191 amino acidresidues. The growth hormone amino acid sequence varies considerably betweenspecies, and non-primate growth hormones have little activity in man. Itsmain function is the stimulation of somatic and bone growth, as well as an increasein the size and mass of organs and tissues.
• Form: Lyophilized in 50 mMAmmonium Bicarbonate.
• Purity: > 98% asdetermined by SDS PAGE analysis.
• Reconstitution: Centrifuge vialprior to opening.Reconstitute with 50 mM Tris, pH 7.5 at 1.0-2.0 mg/ml.
• Contaminants: Human Prl < 0.6%;Human LH < 0.004%; Human FSH < 0.005%; Human TSH < 0.006%.
• Certification: Raw materialstested negative against HBsAg, anti-HIV 1/2, anti-HCV and Syphilis by FDAapproved methods.
• Storage: Store at -20°C. Avoidrepeated freeze-thaw cycles.
• OfficialSymbol: GH1

Gene Information

• Gene Name: GH1 growth hormone 1 [ Homo sapiens]
• Synonyms: GH1; growth hormone1; GH;GHN; GH-N; hGH-N; IGHD1B; somatotropin; pituitary growth hormone
• Gene ID: 2688
• mRNA Refseq: NM_000515
• Protein Refseq: NP_000506
• MIM: 139250
• UniProt ID: P01241
• Chromosome Location: 17q24.2
• Pathway: Adipogenesis;Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction;Diabetes pathways; Endochondral Ossification; Growth hormone receptorsignaling; Immune System; Jak-STAT signaling pathway; Neuroactiveligand-receptor interaction; Synthesis
• Function: growth factoractivity; growth hormone receptor binding; hormone activity; metal ionbinding; prolactin receptor binding; protein binding