Native Human GPX1

Description :	Peroxides in the cell can form highly reactive and damaging free radicals. Glutathione peroxidase (GPO) is a selenoenzyme with peroxidase activity, whose main biological purpose is the elimination of reactive oxygen species to protect the cell.
Source :	Erythrocytes
Species :	Human
Form :	Frozen in 4.3mM sodium phosphate buffer, pH 7.0, containing 0.2mM DTT and sucrose at 0.25 mg/ml.
Unit Definition :	One unit will catalyse oxidation by Hydrogen Peroxide of 1.0 micromole of reduced glutathione to oxidised glutathione per minute at pH 7.0 at 25°C.
Concentration :	>30 U/mg
Reconstitution :	Use of a 0.1M sodium acetate buffer pH 4.5 is recommended.
Tag :	Non

Gene Name	GPX1 glutathione peroxidase 1 [ Homo sapiens ]
Official Symbol	GPX1
Synonyms	GPX1; glutathione peroxidase 1; GPx-1; GSHPx-1; cellular glutathione peroxidase; GPXD; GSHPX1; MGC14399; MGC88245;
Gene ID	2876
mRNA Refseq	NM_000581
Protein Refseq	NP_000572
MIM	138320
UniProt ID	P07203
Chromosome Location	3p21.3
Pathway	Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
Function	SH3 domain binding; endopeptidase inhibitor activity; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity;