Native Human Creatine Kinase, Brain

• Cat.No.: CKB-1177H
• Product Overview: Native human CKB was expressedin Human Brain.

Specification

• Species: Human
• Source: Human Brain
• Tag: Non
• Description: CKB is predominatelyfound in the brain and lungs and injury to either of these organs (forexample, stroke or lung injury due to a pulmonary embolism) are associatedwith elevated levels of CKB. Human Creatine Kinase (CK) enzyme consists oftwo subunits, which can be either B (brain type) or M (muscle type). Threedifferent human isoenzymes exist: CKB, CKMM, and CKMB.
• Form: 1mM DTE, pH 6.5 +25mM Imidazole + 50% Glycerol.
• Purity: 100% CKB by CKElectrophoresis
• Concentration: Typically >1 mgprotein/mL
• Specific Activity: Typically >500U/mL @ 37°C
• Storage: Store at -40°C 1year
• Pathways: Arginine and prolinemetabolism; Creatine metabolism; Creatine pathway; Metabolic pathways; Metabolism;Metabolism of amino acids and derivatives; Urea cycle and metabolism of aminogroups; creatine-phosphate biosynthesis

Gene Information

• Gene Name: CKB creatine kinase, brain [ Homosapiens ]
• Official Symbol: CKB
• Synonyms: CKB; creatine kinase, brain; B-CK; CKBB; creatinekinase B-type; creatine kinase-B; OTTHUMP00000246847; creatine kinase B chain;EC 2.7.3.2; Creatine kinase B-type; Creatine kinase B chain
• Gene ID: 1152
• mRNA Refseq: NM_001823
• Protein Refseq: NP_001814
• MIM: 123280
• UniProt ID: P12277
• Chromosome Location: 14q32.3
• Function: ATPbinding; creatine kinase activity; nucleotide binding