Native Human Coagulation factor X, APC conjugated

• Cat.No.: F10-355H
• Product Overview: Native human F10 was expressed in Human Plasma. Purified protein was labeled with APC in vitro.

Specification

• Description: F10 isactivated into factor Xa by both factor IX (with its cofactor, factor VIII ina complex known as intrinsic Xase) and factor VII with its cofactor, tissuefactor (a complex known as extrinsic Xase). It is therefore the first memberof the final common pathway or thrombin pathway. It acts by cleavingprothrombin in two places, which yields the active thrombin. This process isoptimized when factor Xa is complexed with activated co-factor V in theprothrombinase complex.
• Source: Plasma
• Species: Human
• Conjugation/Label: APC
• Form: Liquid
• Molecular Mass: 46 kDa
• Storage: Store in working aliquots at -20 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: F10 coagulation factor X [ Homo sapiens (human) ]
• Official Symbol: F10
• Synonyms: F10; coagulation factor X; factor Xa; prothrombinase; Stuart-Prower factor; FX; FXA
• Gene ID: 2159
• mRNA Refseq: NM_000504
• Protein Refseq: NP_000495
• MIM: 613872
• UniProt ID: P00742