Native Human CCL25

• Cat.No.: CCL25-31214TH
• Product Overview: Human TECK.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants.
• Tissue specificity: Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
• Form: Lyophilised
• Storage buffer: Preservative: NoneConstituents: 10mM Acetic acid
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: hTECK is a 14.2 kDa protein containing 127 amino acid residues:QGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPK RHRKVCGNPKSREVQRAMKLLDARNKVFAKLHHNMQT FQAGPHAVKKLSSGNSKLSSSKFSNPISSSRKNVSLL ISANSGL
• Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Gene Information

• Gene Name: CCL25 chemokine (C-C motif) ligand 25 [ Homo sapiens ]
• Official Symbol: CCL25
• Synonyms: CCL25; chemokine (C-C motif) ligand 25; SCYA25, small inducible cytokine subfamily A (Cys Cys), member 25; C-C motif chemokine 25; Ck beta 15; Ckb15; TECK; TECKvar; thymus expressed chemokine
• Gene ID: 6370
• mRNA Refseq: NM_001201359
• Protein Refseq: NP_001188288
• MIM: 602565
• Uniprot ID: O15444
• Chromosome Location: 19p13.2
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem
• Function: CCR10 chemokine receptor binding; chemokine activity; hormone activity