Native Cattle RO60 Protein

• Cat.No.: RO60-18C
• Product Overview: TROVE2 is purified from bovine tissues by protein-chemical methods.

Specification

• Species: Bovine
• Source: Bovine tissues
• Description: Ro 60 kDa autoantigen is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA2 may stabilize these RNAs from degradation. Sera taken from patients with Systemic Lupus Erythematosus (SLE) often contains antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.
• Molecular Mass: TROVE2 is a natural protein having a molecular mass of 60 kDa.
• Purity: Greater than 95 % as determined by SDS-PAGE.
• Applications: Western blot with SLE sera (secondary Sjogren’s syndrome).
• Notes: Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
• Stability: Store at 4 centigrade if entire vial will be used within 2-4 weeks.
  Store, frozen at -20 centigrade for longer periods of time.
  Avoid multiple freeze-thaw cycles.
• Concentration: 0.2-0.6 μg/mL (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination.
• Storage Buffer: 20mM Tris/HCl buffer pH-7.5, 150mM NaCl, 2mM MgCl2, 0.2mM DTT, 0.1mM PMSF and 20 % glycerol.
• Shipping: Shipped with Ice Packs

Gene Information

• Gene Name: RO60 Ro60, Y RNA binding protein [ Bos taurus (cattle) ]
• Official Symbol: RO60
• Synonyms: RO60; Ro60, Y RNA binding protein; TROVE2; RNA-binding protein RO60; TROVE domain family member 2
• Gene ID: 518830
• mRNA Refseq: NM_001206183
• Protein Refseq: NP_001193112
• UniProt ID: F1MIZ7