Mouse Anti-IL1RN Monoclonal Antibody
Cat.No. : | DMABT-H18692 |
Product Overview : | Mouse Anti-IL1RN Monoclonal Antibody |
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Species : | Human |
Source : | Mouse |
Tag : | Non |
Antigen Description : | Interleukin-1 receptor antagonist (IL-1RA) is composed of three isoforms, one secreted (sIL-1Ralpha/IL-1Ralpha1), two intracellular (IL-1Ralpha2/IL-1Ralpha3) and produced by monocytes, tissue macrophages, Langerhans cells, dendritic cells, T and B cells, natural killer (NK) cells, large granular lymphocytes (LGL), vascular endothelium, smooth muscle, fibroblasts, thymic epithelia, astrocytes, microglia, glioma cells, keratinocytes, and chondrocytes. It is upregulated by IL-1beta, IL-4, IL-6 and downregulated by glucocorticoids. |
Target : | IL1RN |
Immunogen : | Recombinant human IL-1 receptor antagonist |
Isotype : | IgG1 |
species : | Human |
Clone : | KL2SB-2 |
Conjugation : | N/A |
Applications : | ELISA |
Preparation : | The antibody was purified by affinity chromatography. |
Usage recommendation : | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 4-6 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application. |
Concentration : | 0.5 mg/ml |
Storage : | The antibody solution should be stored undiluted at 4 °C. |
Size : | 50 μg;500 μg |
Gene Name | IL1RN interleukin2receptor antagonist [ Homo sapiens ] |
Official Symbol | IL1RN |
Synonyms | IL1RN; interleukin2receptor antagonist; interleukin-1 receptor antagonist protein; ICIL 1RA; IL 1RN; IL1F3; IL1RA; interleukin2receptor antagonist protein; intracellular interleukin2receptor antagonist; IRAP; MGC10430; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); DIRA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; |
Gene ID | 3557 |
mRNA Refseq | NM_000577 |
Protein Refseq | NP_000568 |
MIM | 147679 |
UniProt ID | P18510 |
Chromosome Location | 2q14.2 |
Pathway | Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; Signaling by Interleukins, organism-specific biosystem; |
Function | interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type II receptor binding; |
◆ Recombinant Proteins | ||
Il1rn-5593M | Recombinant Mouse Interleukin 1 Receptor Antagonist, His-tagged | +Inquiry |
IL1RN-188H | Active Recombinant Human IL1RN protein(Arg26-Glu177) | +Inquiry |
IL1RN-1171H | Recombinant Human IL1RN Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1RN-0278C | Recombinant Cynomolgus IL1RN protein, His-tagged | +Inquiry |
IL1RN-153H | Active Recombinant Human IL1RN Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
IL1RN-1375RCL | Recombinant Rat IL1RN cell lysate | +Inquiry |
IL1RN-2912HCL | Recombinant Human IL1RN cell lysate | +Inquiry |
Not For Human Consumption!
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