Human Protein FGF10 PDB 1nun

• Cat.No.: FGF10-559H
• Product Overview: A DNA sequence encoding the mature form of human FGF10 ( NP_004456.1 ) ( Gln38 - Ser208 ) was expressed.

Specification

• Species: Human
• Source: Human
• Tag: His
• Protein Length: 38-208 a.a.
• Description: The fibroblast growth factors are a growing family of heparin-binding growth factors that that regulate a variety of physiological processes in both developing and adult organism. The secreted human FGF10 exists most abundantly in the embryo and adult lung, and is most closely related to FGF7.
• Form: Supplied as a 0.2 μm filtered solution of 20Mm Tris, pH7.5.
• Purity: > 98 % as determined by SDS-PAGE
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method
• Stability: Samples are stable for up to twelve months from date of receipt at -70°C.
• Predicted N terminal: Met
• Molecular Mass: The recombinant human FGF10 consists of 172 amino acids and has a predicted molecular mass of 19.6 KDa as estimated in SDS-PAGE under reducing conditions.
• Storage: Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Pathways: Downstream signaling of activated FGFR; FGFR ligand binding and activation; FGFR1 ligand binding and activation; FGFR1b ligand binding and activation; FGFR2 ligand binding and activation; FGFR2b ligand binding and activation; FRS2-mediated cascade; Heart Development; IRS-mediated signaling; IRS-related events; Insulin receptor signalling cascade; MAPK signaling pathway; Melanoma; PI-3K cascade; Pathways in cancer

Gene Information

• Gene Name: FGF10 fibroblast growth factor 10 [ Homo sapiens ]
• Official Symbol: FGF10
• Synonyms: FGF10; fibroblast growth factor 10; fibroblast growth factor 10; FGF-10; OTTHUMP00000161804; keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria; Fibroblast growth factor 10; Keratinocyte growth factor 2
• Gene ID: 2255
• mRNA Refseq: NM_004465
• Protein Refseq: NP_004456
• MIM: 602115
• UniProt ID: O15520
• Chromosome Location: 5p13-p12
• Function: chemoattractant activity; protein binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; type 2 fibroblast growth factor receptor binding