Description :	CSTF1, also known as cleavage stimulation factor subunit 1, is involved in the polyadenylation and 3"end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5" UTR, but encoding the same protein, have been found for this gene.
Form :	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 2M urea.
Molecular Mass :	49.4 kDa (439aa)
Protein length :	1-431aa
AA Sequence :	MYRTKVGLKD RQQLYKLIIS QLLYDGYISI ANGLINEIKP QSVCAPSEQL LHLIKLGMEN DDTAVQYAIG RSDTVAPGTG IDLEFDADVQ TMSPEASEYE TCYVTSHKGP CRVATYSRDG QLIATGSADA SIKILDTERM LAKSAMPIEV MMNETAQQNM ENHPVIRTLY DHVDEVTCLA FHPTEQILAS GSRDYTLKLF DYSKPSAKRA FKYIQEAEML RSISFHPSGD FILVGTQHPT LRLYDINTFQ CFVSCNPQDQ HTDAICSVNY NSSANMYVTG SKDGCIKLWD GVSNRCITTF EKAHDGAEVC SAIFSKNSKY ILSSGKDSVA KLWEISTGRT LVRYTGAGLS GRQVHRTQAV FNHTEDYVLL PDERTISLCC WDSRTAERRN LLSLGHNNIV RCIVHSPTNP GFMTCSDDFR ARFWYRRSTT DVEHHHHHH
Purity :	>90% by SDS - PAGE
Applications :	SDS-PAGE
Storage :	Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration :	1 mg/ml (determined by Bradford assay)

Gene Name	CSTF1 cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kDa [ Homo sapiens ]
Official Symbol	CSTF1
Synonyms	CSTF1; cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kDa; cleavage stimulation factor, 3 pre RNA, subunit 1, 50kD; cleavage stimulation factor subunit 1; CF-1 50 kDa subunit; CSTF 50 kDa subunit; cleavage stimulation factor 50 kDa subunit; CstF-50; CstFp50;
Gene ID	1477
mRNA Refseq	NM_001033521
Protein Refseq	NP_001028693
MIM	600369
UniProt ID	Q05048
Chromosome Location	20q13.31
Pathway	BARD1 signaling events, organism-specific biosystem; Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Processing of Capped Intronless Pre-mRNA, organism-specific biosystem; Processing of Intronless Pre-mRNAs, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem;
Function	RNA binding; protein binding;

COA

Cat.No. :	CSTF1-6966H
Product Overview :	Recombinant human CSTF1 protein, fused to His-tag at C-terminus, was expressed in E. coli.

Recombinant Human Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 1, 50kDa, His-tagged