CSTF1
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Official Full Name
cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kDa -
Overview
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. -
Synonyms
CSTF1;cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kDa;cleavage stimulation factor, 3 pre RNA, subunit 1, 50kD;cleavage stimulation factor subunit 1;CF 1 50 kDa subunit;Cleavage stimulation factor 50kDa subunit;Cleavage stimulation factor;Cleavage stimulation factor, 3 prime pre RNA, subunit 1, 50 kD;cleavage stimulation factor, 3 pre RNA, subunit 1, 50kDa;CstF 50;CSTF 50 kDa subunit;CstFp50;OTTHUMP00000031332;CF-1 50 kDa subunit;cleavage stimulation factor 50 kDa subunit;CstF-50
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- T7
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CSTF1 involved in several pathways and played different roles in them. We selected most pathways CSTF1 participated on our site, such as BARD1 signaling events,Cleavage of Growing Transcript in the Termination Region,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSTF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA Polymerase II Transcription Termination | ZFP473,NUDT21,RNPS1,LSM10,THOC4,PAPOLA,ZNF473,LSM11,SRSF11,SLBP |
| BARD1 signaling events | BARD1,CDK2,RBBP8,NPM1,RAD50 |
| Gene Expression | GATAD2A,XPOT,ZNF143A,CCAR1,ZNF227,EEF1G,NRBF2,ZNF221,SUZ12,ZNF18 |
| Processing of Capped Intronless Pre-mRNA | ZFP473,LSM11,NUDT21,CSTF2,SLBP,CSTF3,CLP1,ZNF473,LSM10,PAPOLA |
| Cleavage of Growing Transcript in the Termination Region | LSM11,LSM10,CSTF2,THOC4,CSTF3,RNPS1,SLBP,ZNF473,CLP1,SRSF11 |
| Processing of Intronless Pre-mRNAs | NUDT21,CSTF3,PAPOLA,CLP1,CSTF2 |
| Processing of Capped Intron-Containing Pre-mRNA | HNRNPH1L,SUGP1,NUDT21,CLP1,HNRNPL2,U2AF2,HNRNPA0A,HNRNPD,PTBP1,PCBP2 |
| RNA Polymerase II Transcription | ZNF473,SSRP1A,ZFP473,U2AF2,LSM11,CCNT2A,SUPT16H,GM3258,CSTF2,THOC4 |
Protein Function
CSTF1 has several biochemical functions, for example, RNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSTF1 itself. We selected most functions CSTF1 had, and list some proteins which have the same functions with CSTF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | MOV10B.1,CNOT6,MKI67IP,TARDBP,KHDC3,NCL,RPS7,MBNL1,RNASEL4,CPEB3 |
| protein binding | EPB41L1,WDR4,NCOR2,SENP1,CSF1,MAP4,TSSK6,TDRD1,PSMB2,SOCS7 |
| poly(A) RNA binding | SPATS2,SPATS2L,NPM1,GLTSCR2,HIST2H4,COA6,PRDX1,VSIG8,RPS19BP1,EIF3G |
Interacting Protein
CSTF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSTF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSTF1.
BARD1;TOLLIP;POLR1A;PCNA;USP15;ssrna_uc;1C;Cct8;Cct2;Cct4;FIP1L1;CPSF3
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