| Species : |
Human |
| Source : |
HEK293 |
| Tag : |
Non |
| Description : |
Recombinatant fusion proteins consisting of the extracellular domain of immunoregulatory proteins and the constant (Fc) domain of immunoglobulin G (IgG) represent a growing class of human therapeutics. Chimeric protein of Human target protein and Human IgG-Fc domain can be purified using protein A chromatography. |
| Predicted MolecularMass : |
~ 55 kDa |
| Formulation : |
50µg of recombinant protein in 50µl of 1X PBS, 20%(v/v) glycerol. Frozen solution. |
| Concentration : |
1 mg/mL |
| Purity : |
Greater than 90% by SDS-PAGE and Coomassie blue staining. Western blotting by primary antibody Mouse anti-Human IgG, clone HP6017, Fc and secondary antibody Goat anti-Mouse IgG, HRP conjugate |
| Storage : |
Best stored at -80°C for up to 6 months after date of receipt. Thawed aliquots should be used immediately, as repeated freeze/thaw cycles might result in loss of activity. |
| Background : |
| Introduction | Immunoglobulin G (IgG) is an antibody isotype. It is a protein complex composed of four peptide chains — two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers. Each IgG has two antigen binding sites. Representing approximately 75% of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells. | | Keywords | IgG Fc; IgG Fc(Human); Recombinant Human IgG Fc |
|
