AM580, GMP Grade

• Cat.No.: AM580-15
• Product Overview: AM580 (CD336) (GMP) is AM580 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture.

Specification

• Description: AM580 is a selective RARα agonist.
• Form: Solid, Light brown to yellow
• Target: RAR/RXR
• In Vitro: AM580 (GMP) (0.05 μM) induces mouse embryonic fibroblasts (MEFs) convert into chemically induced pluripotent stem cells (CiPSCs) with the adding in stage I and stage II medium. AM580 (GMP) (0-10 μM; 4 d) induces SH-SY5Y cells develop into neuron-like cells. AM580 (GMP) shows powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. AM580 (GMP) (2.5 μM; 4 d) induces myeloid progenitors develop into neutrophils.
• CAS: 102121-60-8
• Formula: C22H25NO3
• Molecular Mass: 351.44
• Storage: 4 centigrade, protect from light

Gene Information

• Pathway: Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
• Official Symbol: AM580
• Synonyms: AM580; CD336; NSC608001; Ro 40-6055