Active Recombinant Rat RAB3A, Member RAS Oncogene Family, GST-tagged

Cat. No. :	Rab3a-1112R
Description :	Rab3A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab3A is involved in the process of Ca2+ dependent neurotransmitter release. GTP-Rab3A binds effector molecules, Rabphilin-3 and Rim, localized at synaptic vesicles and the active zone, respectively. These complexes facilitate translocation and docking of the synaptic vesicles to the active zone. The GST-Tag facilitates the protein's application in typical GST pull-down assays.
Source :	E. coli.
Usage :	For in vitro use only.
Form :	Liquid. Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol.
Activity :	100 pmol of protein can bind > 80 pmol of GDP.
Purity :	≥ 90% by SDS-PAGE.
Storage :	Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.

Gene Name	Rab3a RAB3A, member RAS oncogene family [ Rattus norvegicus ]
Synonyms	Rab3a; RAB3A, member RAS oncogene family; RAB3; Ras-related small GTP binding protein 3A
Gene ID	25531
mRNA Refseq	NM_013018
Protein Refseq	NP_037150
UniProt ID	P63012
Chromosome Location	16p14
Function	GTP binding; GTPase activity; nucleotide binding; protein binding