Active Recombinant Rat Il4 Protein, His-tagged
Cat.No. : | Il4-245I |
Product Overview : | Recombinant Rat Il4 Protein with a His tag was expressed in CHO. |
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Species : | Rat |
Source : | CHO |
Tag : | His |
Description : | Interleukin-4 (IL-4), also known as BSF-1 and Lymphocyte stimulatory factor 1, is a secreted cytokine belonging to the IL-4/IL-13 family. It is produced by mast cells, T cells and bone marrow stromal cells. IL-4 signals through two receptor complexes: theIL4Rα/common γ chain and the IL4Rα-IL-13 Rα1 receptor complex. IL-4 regulates T cell and B cell proliferation, survival and gene expression. IL-4 also induces IgG and IgE class switching, and the upregulation of MHC-II production. |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 0.2 μg/mL, measured in a proliferationassay using C6 cells. |
Molecular Mass : | 18-22 kDa, observed by reducing SDS-PAGE. |
AA Sequence : | HGCNDSPLREIINTLNQVTEKGTPCTEMFVPDVLTATRNTTENELICRASRVLRKFYFPRDVPPCLKNKSGVLGELRKLCRGVSGLNSLRSCTVNESTLTTLKDFLESLKSILRGKYLQSCTSMSHHHHHH |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant rat Interleukin-4 (IL-4), Hisremains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rat Interleukin-4 (IL-4), Hisshould be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name | Il4 interleukin 4 [ Rattus norvegicus ] |
Official Symbol | Il4 |
Synonyms | IL4; interleukin 4; interleukin-4; IL-4; BSF-1; B-cell growth factor 1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1; B-cell IGG differentiation factor; Il4e12; |
Gene ID | 287287 |
mRNA Refseq | NM_201270 |
Protein Refseq | NP_958427 |
UniProt ID | P20096 |
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Not For Human Consumption!
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