Active Recombinant Rat Il4 Protein, His-tagged

Cat.No. : Il4-245I
Product Overview : Recombinant Rat Il4 Protein with a His tag was expressed in CHO.
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Species : Rat
Source : CHO
Tag : His
Description : Interleukin-4 (IL-4), also known as BSF-1 and Lymphocyte stimulatory factor 1, is a secreted cytokine belonging to the IL-4/IL-13 family. It is produced by mast cells, T cells and bone marrow stromal cells. IL-4 signals through two receptor complexes: theIL4Rα/common γ chain and the IL4Rα-IL-13 Rα1 receptor complex. IL-4 regulates T cell and B cell proliferation, survival and gene expression. IL-4 also induces IgG and IgE class switching, and the upregulation of MHC-II production.
Form : Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity : ED50 < 0.2 μg/mL, measured in a proliferationassay using C6 cells.
Molecular Mass : 18-22 kDa, observed by reducing SDS-PAGE.
AA Sequence : HGCNDSPLREIINTLNQVTEKGTPCTEMFVPDVLTATRNTTENELICRASRVLRKFYFPRDVPPCLKNKSGVLGELRKLCRGVSGLNSLRSCTVNESTLTTLKDFLESLKSILRGKYLQSCTSMSHHHHHH
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE.
Storage : Lyophilized recombinant rat Interleukin-4 (IL-4), Hisremains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rat Interleukin-4 (IL-4), Hisshould be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer : Lyophilized after extensive dialysis against PBS.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/mL.
Gene Name Il4 interleukin 4 [ Rattus norvegicus ]
Official Symbol Il4
Synonyms IL4; interleukin 4; interleukin-4; IL-4; BSF-1; B-cell growth factor 1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1; B-cell IGG differentiation factor; Il4e12;
Gene ID 287287
mRNA Refseq NM_201270
Protein Refseq NP_958427
UniProt ID P20096

Not For Human Consumption!

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