Active Recombinant Rat Cd80, Fc Chimera

• Cat.No.: Cd80-217R
• Product Overview: Recombinant Rat Cd80 (Accession # AAB60503) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Rat
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: Ile39
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to induce IL-2 secretion by Jurkat human acute T cell leukemia cells. Freeman, G.J. et al. (1993) Science 262:909.The ED50 for this effect is typically 0.1 - 0.4 µg/mL in the presence of PHA.
• Molecular Mass: Recombinant Rat Cd80, Fc Chimera has a calculated MW of 50.5 kDa (monomer). In SDS-PAGE migrates as 80-90 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Cd80 Cd80 molecule [ Rattus norvegicus ]
• Official Symbol: Cd80
• Synonyms: CD80; Cd80 molecule; T-lymphocyte activation antigen CD80; CD80 antigen; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); B7-1
• Gene ID: 25408
• mRNA Refseq: NM_012926
• Protein Refseq: NP_037058