Active Recombinant Rabbit Chemokine (C-C Motif) Ligand 2
Cat.No. : | Ccl2-283R |
Product Overview : | Recombinant Rat MCP-1 produced in E.Coli is a non-glycosylated, Polypeptide chain containing 125 amino acids and having a molecular mass of 14092 Dalton. |
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Species : | Rabbit |
Source : | E.coli |
Tag : | Non |
Description : | Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2. CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury, infection, and inflammation. |
Form : | Lyophilized with no additive. |
Purity : | Purity Greater than 95% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Bio-activity : | MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of Rat MCP-1 to chemoattract human peripheral blood at 10-100ng/ml. |
Physical Appearance : | Sterile Filtered white lyophilized (freeze-dried) powder. |
Solubility : | It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. |
Purity Greater than 95% as determined by : | Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Protein Content determined by : | UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
Endotoxin Level : | Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug. |
Amino acid sequence : | QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEW-V QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLT-HKS EANASTLFST TTSSTSVEVT SMTE |
Storage : | Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage. |
Gene Name | Ccl2 chemokine (C-C motif) ligand 2 [ Rattus norvegicus ] |
Official Symbol | Ccl2 |
Synonyms | Ccl2; chemokine (C-C motif) ligand 2; MCP-1; Scya2; Sigje;monocyte chemotactic protein 1; small inducible cytokine A2; monocyte chemoattractant protein-1; Small inducible gene JE |
Gene ID | 24770 |
mRNA Refseq | NM_031530 |
Protein Refseq | NP_113718 |
UniProt ID | P14844 |
Chromosome Location | 10q26 |
Pathway | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Function | CCR2 chemokine receptor binding; G-protein-coupled receptor binding; heparin binding; protein binding |
◆ Recombinant Proteins | ||
CCL2-2950HF | Recombinant Full Length Human CCL2 Protein, GST-tagged | +Inquiry |
CCL2-78H | Recombinant Human CCL2 | +Inquiry |
Ccl2-1101R | Recombinant Rat Ccl2 Protein, His-tagged | +Inquiry |
CCL2-2147P | Recombinant Pig CCL2 Protein, His-tagged | +Inquiry |
CCL2-683R | Recombinant Rhesus monkey CCL2 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
Not For Human Consumption!
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