Active Recombinant Mouse Tie1 Protein, His-tagged

• Cat.No.: Tie1-7352M
• Product Overview: Recombinant Mouse soluble TIE-1 was fused with a 6x His-tag at the C-terminus was expressed in insect cells.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: His
• Description: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
• Form: Lyophilized
• Bio-activity: Since a ligand for TIE-1 has not yet been identified, the recombinant protein was not tested for biological activity.
• Molecular Mass: 95 kDa
• AA Sequence: SVDLTLLANLRITDPQRFFLTCVSGEAGAGRSSDPPLLLEKDDRIVRTFPPGQPLYLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVLYVHNSPGAHLFPDKVTHTVNKGDTAVLSAHVHKKQTDVIWKNNGSYFNTLDWQEADDGRFQLQLQNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCVKDCPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGTAGCGLTFCLPDPYGCSCGSGWRGSQCQEACAPDHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILSMATEVEFNIGTMPRINCAAAGNPFPVRGSMKLRKPDGTMLLSTKVIVEPDRTAEFEVPSLTLGDSGFWECRVSTSGGQDSRRFKVNVKVPPVPLTAPRLLAKQSRQLVVSPLVSFSGDGPISSVRLHYRPQDSTIAWSAIVVDPSENVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGPALMTTDCPEPLLQPWLESWHVEGPDRLRVSWSLPSVPLSGDGFLLRLWDGARGQERRENISFPQARTALLTGLTPGTHYQLDVRLYHCTLLGPASPPAHVHLPPSGPPAPRHLHAQALSDSEIQLMWHPEAPSGPISKYIVEIQVAGGSGDPQWMDVDRPEETSIIVRGLNASTRYLFRVRASVQGLGDWSNTVEEATLGNGLQSEDPVRESRATRHHHHHH
• Endotoxin: < 0.1 ng/μg sTIE-1
• Purity: > 90 %
• Stability: Samples are stable for 2-4 weeks at 2-8 centigrade.
• Storage: sTIE-1 should be stored in working aliquots at -20 to -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS without stabilizers
• Reconstitution: The lyophilized sTIE-1 is soluble in water and most aqueous buffers. The lyophilized sTIE-1 should be restored in PBS or medium to a concentration not lower than 50 μg/mL.

Gene Information

• Gene Name: Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tie1
• Synonyms: Tie1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TI; TIE; tie-; tie-1; D430008P04Rik; tyrosine-protein kinase receptor Tie-1; tyrosine kinase receptor 1; EC 2.7.10.1
• Gene ID: 21846
• mRNA Refseq: NM_011587
• Protein Refseq: NP_035717
• UniProt ID: Q06806