Active Recombinant Mouse Siglece, Fc Chimera

• Cat.No.: Siglece-314M
• Product Overview: Recombinant Mouse Siglece (Accession # AAH23280) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: No results obtained, N-sequencing might be blocked: Gln20 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When 0.5 µg/mL of Recombinant Mouse Siglec-E Fc Chimera is immobilized onto a goat anti-mouse IgG Fc antibody coated plate, the concentration of biotinylated Neu5Ac alpha 2-6GalNAc alpha -Polyacrylamide that produces 50% of the optimal binding response is found to be approximately 20 - 80 ng/mL.
• Molecular Mass: Recombinant Mouse Siglece, Fc Chimera has a calculated MW of 64.6 kDa (monomer). In SDS-PAGE migrates as 75-95 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Siglece sialic acid binding Ig-like lectin E [ Mus musculus (house mouse) ]
• Official Symbol: Siglece
• Synonyms: Siglece; sialic acid binding Ig-like lectin E; Cd170; Siglec5; Siglec9; Siglec12; Siglecl1; mSiglec-E; sialic acid-binding Ig-like lectin 12; MIS; SIGLEC-like 1; myeloid inhibitory siglec; sialic acid binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 5; sialic acid-binding Ig-like lectin E; sialic acid-binding Ig-like lectin-like 1; sialic acid-binding immunoglobulin-like lectin E; siglec-12; siglec-5; siglec-E; siglec-L1
• Gene ID: 83382
• mRNA Refseq: NM_031181
• Protein Refseq: NP_112458
• UniProt ID: Q91Y57
• Chromosome Location: 7; 7 B2