Active Recombinant Mouse RAB18 Protein, GST/His-tagged

• Cat.No.: RAB18-712M
• Product Overview: Recombinant Mouse RAB18 protein was expressed in E. coli with GST-His tag.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Description: Rab18A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab18A is localized in dense apical tubules (kidney) and basolateral membrane (intestine) as well as lipid droplets in ER and neuroendocrine secretory granules. The enzyme is involved in the formation of lipid droplets form ER. Furthermore it is a negative regulator of neuroendocrine secretion. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.
• Form: 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol
• Bio-activity: 100 pmol of protein can bind > 80 pmol of GDP.
• Purity: > 90 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: Rab18 RAB18, member RAS oncogene family [ Mus musculus ]
• Official Symbol: RAB18
• Synonyms: AA959686
• Gene ID: 19330
• mRNA Refseq: NM_181070.5
• Protein Refseq: NP_851415
• UniProt ID: P35293