Active Recombinant Mouse Pim3, GST-tagged
Cat.No. : | Pim3-1081M |
Product Overview : | Recombinant full-length mouse PIM3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Species : | Mouse |
Source : | Sf9 Cells |
Tag : | GST |
Protein Length : | Full Length |
Description : | PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases. Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. Pim-3 also expressed in human pancreatic cancer cell and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines. |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 785 nmol/min/mg |
Molecular Mass : | ~63 kDa |
Purity : | >90% |
Applications : | Kinase Assay; Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name | Pim3?proviral integration site 3 [?Mus musculus?(house mouse) ] |
Official Symbol | Pim3 |
Synonyms | Pim3; proviral integration site 3; Kid1; BC026639; serine/threonine-protein kinase pim-3; KID-1/kinase induced by depolarization; NP_663453.1; EC 2.7.11.1 |
Gene ID | 223775 |
mRNA Refseq | NM_145478 |
Protein Refseq | NP_663453 |
UniProt ID | P58750 |
Chromosome Location | 15 E3; 15 |
Function | ATP binding; kinase activity; protein binding; protein serine/threonine kinase activity |
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Not For Human Consumption!
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