Active Recombinant Mouse Ncam1, His tagged

Cat.No. : Ncam1-112M
Product Overview : Recombinant Mouse Ncam1 (Met1-Thr711) fused with?6-His tag at C-terminal, was expressed in Mouse?NSO?Cells.
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Description : Neural Cell Adhesion Molecule?(NCAM, also thecluster of differentiationCD56) is a homophilic binding glycoprotein expressed on the surface of?neurons,?glia,skeletal muscle?and?natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion,?neurite outgrowth, synaptic plasticity, and learning and memory.
Source : Mammalian cells
Species : Mouse
Tag : His
Predicted N Terminal : Leu20
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of Neuro?2A mouse neuroblastoma cells. When 5 x 104 cells/well are added to mouse NCAM-1 coated plates (25 μg/mL with 100 μL/well), >20% will adhere after 1 hour incubation at 37 °C.
Molecular Mass : 77.4 kDa
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in PBS.
Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Protein length : 1-711 a.a.
Gene Name Ncam1 neural cell adhesion molecule 1 [ Mus musculus ]
Official Symbol Ncam1
Synonyms NCAM1; neural cell adhesion molecule 1; N-CAM-1; CD56; Ncam; E-NCAM; NCAM-1;
Gene ID 17967
mRNA Refseq NM_001081445
Protein Refseq NP_001074914
Pathway Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem;
Function LRR domain binding; heparin binding; phosphatase binding;

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