Active Recombinant Mouse Ncam1, His tagged
Cat.No. : | Ncam1-112M |
Product Overview : | Recombinant Mouse Ncam1 (Met1-Thr711) fused with?6-His tag at C-terminal, was expressed in Mouse?NSO?Cells. |
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Description : | Neural Cell Adhesion Molecule?(NCAM, also thecluster of differentiationCD56) is a homophilic binding glycoprotein expressed on the surface of?neurons,?glia,skeletal muscle?and?natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion,?neurite outgrowth, synaptic plasticity, and learning and memory. |
Source : | Mammalian cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Leu20 |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of Neuro?2A mouse neuroblastoma cells. When 5 x 104 cells/well are added to mouse NCAM-1 coated plates (25 μg/mL with 100 μL/well), >20% will adhere after 1 hour incubation at 37 °C. |
Molecular Mass : | 77.4 kDa |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Protein length : | 1-711 a.a. |
Gene Name | Ncam1 neural cell adhesion molecule 1 [ Mus musculus ] |
Official Symbol | Ncam1 |
Synonyms | NCAM1; neural cell adhesion molecule 1; N-CAM-1; CD56; Ncam; E-NCAM; NCAM-1; |
Gene ID | 17967 |
mRNA Refseq | NM_001081445 |
Protein Refseq | NP_001074914 |
Pathway | Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem; |
Function | LRR domain binding; heparin binding; phosphatase binding; |
Not For Human Consumption!
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