Active Recombinant Mouse Interleukin 17 receptor C, His-tagged

• Cat.No.: Il17rc-5648M
• Product Overview: RecombinantMouse Il17rc protein was expressed in Murine myeloma cellline. Leu21-Trp465,with a C-terminal 6-His tag.

Specification

• Cat. No.: Il17rc-5648M
• Description: Il17rc isan 85-110 kDa member of the IL-17 receptor family. This is one of fivefamilies, termed IL-17 RA, B, C, D and E that comprise the cytokine receptorsuperfamily. Not all receptors appear to bind known members of the IL-17cytokine family. To date, IL-17 RA is reported to bind IL-17A, while IL-17 RBis reported to bind IL-17B and IL-17E. Mouse Il17rc is a type I transmembraneglycoprotein that is expressed on a variety of nonhematopoietic cell types.Full-length Il17rc is synthesized as a 674 amino acid (aa) precursor.
• Source: Mammalian cells
• Form: Lyophilized from a0.2 um filtered solution in PBS.
• N-terminalSequence: Leu21
• MolecularWeight: 50.5 kDa
• Activity: Measuredby its ability to bind rmIL-17F in a functional ELISA with an estimated KD< 3 nM.
• Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
• SDS-PAGE: 75-85kDa, reducing conditions.
• Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: 200 μg/mLin sterile PBS
• Storage: Use a manual defrost freezer and avoid repeated freeze-thawcycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
• Protein length: 21-465 a.a.

Gene Information

• Gene Name: Il17rc interleukin 17 receptorC [ Mus musculus ]
• Official Symbol: Il17rc
• Synonyms: Il17rc; interleukin17 receptor C; Il17rl; IL-17RC; IL17-RC; IL17-RL; 1110025H02Rik;zcytoR14; IL-17 receptor C; interleukin-17 receptor-like protein; Putative uncharacterized protein
• Gene ID: 171095
• mRNA Refseq: NM_134159
• Protein Refseq: NP_598920
• UniProt ID: Q60837
• Chromosome Location: 6
• Function: molecular_function;receptor activity