Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein 7, His-tagged

Cat.No. : Igfbp7-5645M
Product Overview : RecombinantMouse Igfbp7 protein was expressed in Spodopterafrugiperda. Ser28-Leu281,with an N-terminal 10-His tag.
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Species : Mouse
Source : S.frugiperda
Tag : His
Protein Length : 28-281 a.a.
Description : Igfbp7 isa 31-37 kDa secreted glycoprotein that belongs to the IGFBP superfamily ofmolecules. Members of this superfamily are characterized by the presence of10-12 conserved cysteines in the first third of the molecule, and the partialconservation of an xCGCCxxC octapeptide motif that exists in an N-terminalIGFBP domain. Mouse Igfbp7 cDNA encodes a 281 amino acid (aa) precursorprotein that contains a putative 25 aa signal peptide and a 256 aa matureregion.
Form : Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence : His
MolecularWeight : 27.5 kDa
Activity : Measuredby its ability to bind 6Ckine/CCL21 in a functional ELISA. When rmIGFBP-rp1/Igfbp7 isImmobilized at 500 ng/mL (10 μL/well), the concentration of rhCCL21/6Ckinethat produces 50% optimal binding response is found to be approximately 4-20ng/mL.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 35 kDa,reducing conditions.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 100 μg/mLin sterile PBS
Storage : Use a manual defrost freezer and avoid repeated freeze-thawcycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name Igfbp7 insulin-like growth factorbinding protein 7 [ Mus musculus ]
Official Symbol Igfbp7
Synonyms Igfbp7; insulin-likegrowth factor binding protein 7; AGM;Fstl2; Mac25; insulin-like growth factor-binding protein 7; IBP-7; IGFBP-7;angiomodulin; IGF-binding protein 7
Gene ID 29817
mRNA Refseq NM_001159518
Protein Refseq NP_001152990
UniProt ID Q61581
Chromosome Location 5
Pathway Senescence andAutophagy
Function growth factorbinding; insulin-like growth factor binding

Not For Human Consumption!

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