Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein 7, His-tagged
Cat.No. : | Igfbp7-5645M |
Product Overview : | RecombinantMouse Igfbp7 protein was expressed in Spodopterafrugiperda. Ser28-Leu281,with an N-terminal 10-His tag. |
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Species : | Mouse |
Source : | S.frugiperda |
Tag : | His |
Protein Length : | 28-281 a.a. |
Description : | Igfbp7 isa 31-37 kDa secreted glycoprotein that belongs to the IGFBP superfamily ofmolecules. Members of this superfamily are characterized by the presence of10-12 conserved cysteines in the first third of the molecule, and the partialconservation of an xCGCCxxC octapeptide motif that exists in an N-terminalIGFBP domain. Mouse Igfbp7 cDNA encodes a 281 amino acid (aa) precursorprotein that contains a putative 25 aa signal peptide and a 256 aa matureregion. |
Form : | Lyophilized from a0.2 um filtered solution in PBS. |
N-terminalSequence : | His |
MolecularWeight : | 27.5 kDa |
Activity : | Measuredby its ability to bind 6Ckine/CCL21 in a functional ELISA. When rmIGFBP-rp1/Igfbp7 isImmobilized at 500 ng/mL (10 μL/well), the concentration of rhCCL21/6Ckinethat produces 50% optimal binding response is found to be approximately 4-20ng/mL. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 35 kDa,reducing conditions. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mLin sterile PBS |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thawcycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name | Igfbp7 insulin-like growth factorbinding protein 7 [ Mus musculus ] |
Official Symbol | Igfbp7 |
Synonyms | Igfbp7; insulin-likegrowth factor binding protein 7; AGM;Fstl2; Mac25; insulin-like growth factor-binding protein 7; IBP-7; IGFBP-7;angiomodulin; IGF-binding protein 7 |
Gene ID | 29817 |
mRNA Refseq | NM_001159518 |
Protein Refseq | NP_001152990 |
UniProt ID | Q61581 |
Chromosome Location | 5 |
Pathway | Senescence andAutophagy |
Function | growth factorbinding; insulin-like growth factor binding |
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IGFBP7-2280H | Recombinant Human IGFBP7 Protein, His-tagged | +Inquiry |
IGFBP7-1630H | Recombinant Human IGFBP7, His-tagged | +Inquiry |
IGFBP7-1605H | Active Recombinant Human IGFBP7 protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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