Active Recombinant Mouse Inhba Protein

• Cat.No.: Inhba-01M
• Product Overview: Active form Activin-A Murine Recombinant produced in E. coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2 kDa. The Active form Activin-A is purified by standard chromatographic techniques.

Specification

• Species: Mouse
• Source: E.coli
• Description: This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Homozygous knockout mice for this gene lack whiskers and exhibit tooth and palate defects, leading to neonatal lethality.
• Form: Lyophilized freeze dried powder.
• Bio-activity: Biological activity is assessed by the ability to induce cytoxicity of MPC-11 cells and was found to be 8.8 ng/mL corresponding to a specific activity of 1.1 x 105 units/mg.
• Molecular Mass: 26.2 kDa
• AA Sequence: MGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
• Purity: >95%
• Usage: Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
• Storage: Lyophilized Activin-A although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution Activin-A should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.
  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  Please prevent freeze-thaw cycles.
• Storage Buffer: Mouse Activin-A lyophilized from a concentrated 1 mg/mL protein solution containing 0.1% TFA.
• Reconstitution: Murine INHBA protein should be reconstituted in distilled pyrogen free water to a concentration of 100 μg/mL which can then be further diluted to other aqueous solutions.
• Shipping: Shipped at room temperature.

Gene Information

• Gene Name: Inhba inhibin beta-A [ Mus musculus (house mouse) ]
• Official Symbol: Inhba
• Synonyms: Inhba; inhibin beta-A; inhibin beta A chain; activin A; activin beta-A chain
• Gene ID: 16323
• mRNA Refseq: NM_008380
• Protein Refseq: NP_032406
• UniProt ID: Q04998