Active Recombinant Mouse Il4 Protein (HIs21-Ser140), C-His tagged, Animal-free, Carrier-free
Cat.No. : | Il4-59M |
Product Overview : | Recombinant Mouse Il4 Protein (HIs21-Ser140) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
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Species : | Mouse |
Source : | E.coli |
Tag : | His |
Protein Length : | HIs21-Ser140 |
Description : | Interleukin-4 (IL-4) is a key cytokine produced by activated T cells, mast cells, basophils, neutrophils and eosinophils. IL-4 is critical for the development of Th2-mediated responses, which is related to allergy and asthma. It can also regulate B cell responses, including survival, cell proliferation and gene expression. IL-4 also plays fundamental role for B-cell stimulation, including induction of the IgE isotype switch. |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce HT-2 cells proliferation. The ED50 for this effect is < 1 ng/mL. The specific activity of recombinant mouse IL-4 is approximately >1 × 10⁶ IU/mg. |
Molecular Mass : | The protein has a calculated MW of 14.5 kDa. The protein migrates as 14 kDa under reducing condition (SDS-PAGE analysis). |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name | Il4 interleukin 4 [ Mus musculus (house mouse) ] |
Official Symbol | Il4 |
Synonyms | IL4; interleukin 4; interleukin-4; IGG1 induction factor; B-cell growth factor 1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1; B-cell IgG differentiation factor; Il-4; BSF-1; |
Gene ID | 16189 |
mRNA Refseq | NM_021283 |
Protein Refseq | NP_067258 |
UniProt ID | P07750 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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