Active Recombinant Mouse Il36g Protein (Gly13-Ser164), C-His tagged, Animal-free, Carrier-free

• Cat.No.: Il36g-81M
• Product Overview: Recombinant Mouse Il36g Protein (Gly13-Ser164) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Gly13-Ser164
• Description: Interleukin 36 gamma (IL-36 gamma) is a 17.65 kDa cytokine with 159 amino acid residues. IL-36 gamma is a member of the IL-1 family and is mainly expressed in keratinocytes, bronchial epithelial cells, macrophages, and monocyte. This cytokine responds to multiple pathogen-associated molecular patterns (PAMPs) and participates in the inflammatory response. In addition, it also induces the production of pro-inflammatory cytokines like IL-12, IL-1β, IL-6, TNF-α, and IL-23.
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is < 15 ng/mL. The specific activity of recombinant mouse IL-36 gamma is > 6 × 10^⁴ IU/mg.
• Molecular Mass: The protein has a calculated MW of 18.27 kDa.
  The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis).
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: Il36g interleukin 36G [ Mus musculus (house mouse) ]
• Official Symbol: Il36g
• Synonyms: Il36g; interleukin 36G; If36g; Il1f9; IL-36gamma; interleukin-36 gamma; IL-1F9; interleukin 1 family, member 9
• Gene ID: 215257
• mRNA Refseq: NM_153511
• Protein Refseq: NP_705731
• UniProt ID: Q8R460