Active Recombinant Mouse IL10, MIgG2a Fc-tagged, mutant

• Cat.No.: IL10-002M
• Product Overview: The extracellular domain of mouse IL-10 (AAI37845.1)(Met1-Ser178) is fused to the N-terminus of the Fc region of mutant mouse IgG2a was expressed in CHO cell.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Protein Length: 1-178 a.a.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: 6,000 units/µg as determined by ELISA. Bioactivity demonstrated in cytokine synthesis inhibition assay, measuring inhibition of IL-6 production by PU5-1 cells.
• Molecular Mass: 45KDa (monomer)
• AA Sequence: Met1-Ser178
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Il10 interleukin 10 [ Mus musculus ]
• Official Symbol: IL10
• Synonyms: IL10; interleukin 10; interleukin-10; cytokine synthesis inhibitory factor; CSIF; Il-10
• Gene ID: 16153
• mRNA Refseq: NM_010548
• Protein Refseq: NP_034678
• Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Asthma, organism-specific biosystem
• Function: cytokine activity; cytokine activity; interleukin-10 receptor binding