Active Recombinant Mouse FCGRT & B2M Protein, His-tagged

• Cat.No.: FCGRT & B2M-1249M
• Product Overview: Recombinant extracellular domain (Met 1-Ser 297) of human FCGRT (P55899) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; Recombinant human B2M (P61769) (Met 1-Met 119) constructed the plasmid 2. The two plasmids were co-ex

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: 1-297;1-119 a.a.
• Predicted N Terminal: Ala 24 & Ile 21
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its ability to bind human IgG1 in functional ELISA.
• Molecular Mass: The recombinant heterodimer of human FCGRT / B2M comprises 385 ( 285 + 100 ) amino acids and has a calculated molecular mass of 43.5 ( 31.8 + 11.7 ) kDa. The apparent molecular mass of rh FCGRT / B2M heterodimer is approximately 35 & 12 kDa respectively in SDS-PAGE under reducing conditions
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Fcgrt Fc receptor, IgG, alpha chain transporter [ Mus musculus ]
• Official Symbol: FCGRT
• Synonyms: FCGRT; Fc receptor, IgG, alpha chain transporter; IgG receptor FcRn large subunit p51; neonatal Fc receptor; igG Fc fragment receptor transporter alpha chain; FcRn
• Gene ID: 14132
• mRNA Refseq: NM_010189
• Protein Refseq: NP_034319
• Function: IgG binding; beta-2-microglobulin binding; receptor activity