Active Recombinant Mouse Fc receptor-like B, His-tagged

• Cat.No.: Fcrlb-509M
• Product Overview: RecombinantMouse Fcrlb protein was expressed in Murine myeloma cellline. Ala18-Ser427,with a C-terminal 6-His tag.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• ProteinLength: 18-427 a.a.
• Description: Fcrlb is a 60kDa protein with sequence homology to classical Fc receptors. There are atleast six type 1 transmembrane FCRL proteins and two that lack transmembranesegments. Each family member contains between three and nine immunoglobulin-likedomains. FCRL proteins are differentially expressed within the B cell lineageand can either promote or inhibit B cell proliferation and activation. Accordingto R&D Systems testing, Fcrlb binds to purifiedmouse IgG. Mouse Fcrlb shares 82% and 94% aa sequence identitywith human and rat Fcrlb, respectively. It contains a putativesignal peptide, three immunoglobulinlik domains, and a mucinlike stalk thatis rich in Pro, Ser, and Thr residues.
• Form: Lyophilized from a0.2 um filtered solution in PBS.
• N-terminalSequence: Ala18
• MolecularWeight: 46.5 kDa (monomer)
• Activity: Measuredby its ability to bind mouse IgG with an estimated KD < 300 nM.
• Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
• SDS-PAGE: 60-70kDa, reducing conditions.
• Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstitute at100μg/mL in PBS.
• Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.

Gene Information

• Gene Name: Fcrlb Fc receptor-like B [ Musmusculus ]
• Official Symbol: Fcrlb
• Synonyms: Fcrlb; Fcreceptor-like B; Fcry; FREB2; FcRL2; FREB-2; Fcrlm2; mFCRL2; Fcreceptor-like B; Fc receptor related Y; fc receptor-like protein 2; Fcreceptor-like mucin-like 2; fc receptor-related protein Y; fc receptor-likeand mucin-like protein 2; fc receptor homolog expressed in B cells protein 2
• Gene ID: 435653
• mRNA Refseq: NM_001029984
• Protein Refseq: NP_001025155
• UniProt ID: Q5DRQ8
• Chromosome Location: 1
• Function: molecular_function