Active Recombinant Mouse Dll1 protein, Fc-tagged

• Cat.No.: Dll1-2562M
• Product Overview: Recombinant Mouse Dll1(aa 1-545) fused with Fc portion of human IgG1 at C-terminal was expressed in HEK293.

Specification

• Description: The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
• Source: HEK 293
• Species: Mouse
• Tag: Fc
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Bio-activity: Inhibits adipogenesis of 3T3L-1 cells. Induces Hes-1 in 3T3L-1 cells.
• Molecular Mass: ~100kDa (SDS-PAGE)
• Endotoxin: 0.1EU/μg purified protein (LAL test; Lonza).
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Storage: Short Term Storage: +4 centigrade;Long Term Storage: -20 centigrade;Handling Advice After opening, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles.
• Concentration: 1mg/ml
• Protein length: 1-545 a.a.

Gene Information

• Gene Name: Dll1 delta-like 1 (Drosophila) [ Mus musculus ]
• Official Symbol: Dll1
• Synonyms: DLL1; delta-like 1 (Drosophila); delta-like protein 1; delta like-1; drosophila Delta homolog 1; Delta1
• Gene ID: 13388
• mRNA Refseq: NM_007865
• Protein Refseq: NP_031891
• UniProt ID: Q61483
• Chromosome Location: 17 A2; 17 8.95 cM
• Pathway: Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem
• Function: Notch binding; Notch binding; calcium ion binding; protein binding