Active Recombinant Mouse Dipeptidylpeptidase 4, His-tagged

• Cat.No.: Dpp4-413M
• Product Overview: Recombinantmouse Dpp4 protein was expressed in Murine myeloma cell line, NS0-derived, with a C-terminal9-His tag.Ser29-His760.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: 29-760 a.a.
• Description: Dpp4 is a serineexopeptidase that releases Xaa-Pro dipeptides from the N-terminus of oligo- andpolypeptides. It is a type II membrane protein consisting of a shortcytoplasmic tail, a transmembrane domain, and a long extracellular domain.
• Form: Lyophilized from a0.2 μm filtered solution in Tris and Nacl.
• N-terminal Sequence: Ser29
• Molecular Weight: 86 kDa
• Activity: Measured by itsability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin(GP-AMC). The specific activity is > 2,500 pmoles/min/μg, as measuredunder the described conditions. See Activity Assay Protocol.
• Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
• Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution.

Gene Information

• Gene Name: Dpp4dipeptidylpeptidase 4 [ Mus musculus ]
• Official Symbol: Dpp4
• Synonyms: Dpp4; dipeptidylpeptidase4; Cd26;THAM; Dpp-4; OTTMUSP00000013700;dipeptidyl peptidase 4; DPP IV; dipeptidyl peptidase IV; thymocyte-activatingmolecule; T-cell activation antigen CD26; EC 3.4.14.5; CD26
• Gene ID: 13482
• mRNA Refseq: NM_010074
• Protein Refseq: NP_034202
• UniProt ID: P28843
• Chromosome Location: 2
• Pathway: Incretin Synthesis, Secretion, andInactivation; Integration of energy metabolism; Metabolism; Protein digestionand Incretin Synthesis, Secretion, and Inactivation; Integration of energymetabolism; Metabolism; Protein digestion and absorption; Regulation ofInsulin Secretion; Synthesis, Secretion, and Inactivation of Glucagon-likePeptide-1 (GLP-1)
• Function: aminopeptidase activity; collagen binding;dipeptidyl-peptidase activity; hydrolase activity; peptidase activity;peptide binding; protease binding; protein homodimerization activity;receptor activity; receptor binding; serine-type endopeptidase activity;serine-type peptidase activity