Active Recombinant Mouse Crlf2, Fc Chimera

• Cat.No.: Crlf2-450M
• Product Overview: Recombinant Mouse Crlf2 (Accession # BAA92159) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: Fc
• Predicted N Terminal: Ala20
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit TSLP-dependent proliferation of BaF3 mouse pro-B cells transfected with mouse IL-7 R alpha.The ED50 for this effect is typically 2 - 8 µg/mL in the presence of 7.5 ng/mL of rmTSLP.
• Molecular Mass: Recombinant Mouse Crlf2, Fc Chimera has a calculated MW of 49.3 kDa (monomer). In SDS-PAGE migrates as 65 - 80 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Crlf2 cytokine receptor-like factor 2 [ Mus musculus ]
• Official Symbol: Crlf2
• Synonyms: CRLF2; cytokine receptor-like factor 2; CRLM-2; delta 1; TSLP receptor; lymphocyte antigen 114; type I cytokine receptor delta 1; cytokine receptor-like molecule 2; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; CRLM2; Ly114; Tpte2; Tslpr
• Gene ID: 57914
• mRNA Refseq: NM_001164735
• Protein Refseq: NP_001158207