Active Recombinant Mouse CD80, MIgG2a Fc-tagged

• Cat.No.: CD80-626M
• Product Overview: The extracellular domain of mouse CD80 [B7-1] (NP_033985.3) (Asp37 - Lys245) is fused to the N-terminus of the Fc region of mouse IgG2a.

Specification

• Source: CHO cells
• Species: Mouse
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to induce IL-2 secretion by Jurkat human acute T cell leukemia cells.
• Molecular Mass: 50 KDa (monomer)
• AA Sequence: Asp37 - Lys245
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.
• Protein length: 37-245 a.a.

Gene Information

• Gene Name: Cd80 CD80 antigen [ Mus musculus ]
• Official Symbol: CD80
• Synonyms: CD80; CD80 antigen; T-lymphocyte activation antigen CD80; B7 protein; activation B7-1 antigen; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17
• Gene ID: 12519
• mRNA Refseq: NM_009855
• Protein Refseq: NP_033985
• Pathway: Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem
• Function: protein binding; receptor activity