Active Recombinant Mouse CD28, MIgG2a Fc-tagged

Cat.No. : CD28-232M
Product Overview : The extracellular domain of mouse CD28 (NP_031668.3) (Lys21-Lys149) is fused to the N-terminus of the Fc region of mouse IgG2a.
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Species : Mouse
Source : CHO
Tag : Fc
Protein Length : 21-149 a.a.
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells.
Molecular Mass : 41 KDa (monomer)
AA Sequence : Lys21-Lys149
Endotoxin : <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name Cd28 CD28 antigen [ Mus musculus ]
Official Symbol CD28
Synonyms CD28; CD28 antigen; T-cell-specific surface glycoprotein CD28;
Gene ID 12487
mRNA Refseq NM_007642
Protein Refseq NP_031668
Pathway Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem;
Function SH3/SH2 adaptor activity; protease binding; protein homodimerization activity;

Not For Human Consumption!

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