Active Recombinant Mouse CD28, MIgG2a Fc-tagged
Cat.No. : | CD28-232M |
Product Overview : | The extracellular domain of mouse CD28 (NP_031668.3) (Lys21-Lys149) is fused to the N-terminus of the Fc region of mouse IgG2a. |
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Species : | Mouse |
Source : | CHO |
Tag : | Fc |
Protein Length : | 21-149 a.a. |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. |
Molecular Mass : | 41 KDa (monomer) |
AA Sequence : | Lys21-Lys149 |
Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name | Cd28 CD28 antigen [ Mus musculus ] |
Official Symbol | CD28 |
Synonyms | CD28; CD28 antigen; T-cell-specific surface glycoprotein CD28; |
Gene ID | 12487 |
mRNA Refseq | NM_007642 |
Protein Refseq | NP_031668 |
Pathway | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; |
Function | SH3/SH2 adaptor activity; protease binding; protein homodimerization activity; |
◆ Cell & Tissue Lysates | ||
CD28-2002MCL | Recombinant Mouse CD28 cell lysate | +Inquiry |
CD28-2013HCL | Recombinant Human CD28 cell lysate | +Inquiry |
Not For Human Consumption!
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