Active Recombinant Mouse Adipoq, FLAG-tagged

• Cat.No.: Adipoq-79M
• Product Overview: Mouse adiponectin (aa 18-247) is fused at the N-terminus to a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 18-247 a.a.
• Description: ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Bio-activity: Induces the phosphorylation of acetyl-CoA carboxylase (ACC) in C2C12 cells.
• Molecular Mass: ~30kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: Adipoq adiponectin, C1Q and collagen domain containing [ Mus musculus ]
• Official Symbol: Adipoq
• Synonyms: ADIPOQ; adiponectin, C1Q and collagen domain containing; adiponectin; adipocyte-specific protein AdipoQ; adipocyte complement related protein; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30
• Gene ID: 11450
• mRNA Refseq: NM_009605
• Protein Refseq: NP_033735
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Leptin and adiponectin, organism-specific biosystem; PPAR (Peroxisome proliferator-activated receptor) signaling pathway, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem
• Function: eukaryotic cell surface binding; hormone activity; hormone activity; hormone activity; protein binding; protein homodimerization activity; receptor binding; sialic acid binding